HI, try some tweaks:
- First Create System Restore Point
https://www.elevenforum.com/t/create...ndows-11.3602/
- Disable Core Parking
https://bitsum.com/parkcontrol/
- Disable Windows Hibernate
https://www.tenforums.com/tutorials/...dows-10-a.html
- Disable Core Isolation and Memory Integrity. (Use the registry)
https://www.elevenforum.com/t/enable...ndows-11.4942/
- Disable Widgets
https://www.elevenforum.com/t/enable...ndows-11.1196/
- Disable Microsoft Edge from running in background
https://www.windowscentral.com/how-p...und-windows-10
Maybe disable the other stuff too
https://www.oo-software.com/en/shutup10
- Set the Windows Priority Separation to 26hex
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\PriorityControl]
"Win32PrioritySeparation"=dword:00000026
https://www.thewindowsclub.com/proce...in-windows-7-8
Or double click the REG file
https://drive.google.com/file/d/1ckl...usp=drive_link
- Set the currently active power scheme to Processor performance time check interval = 5000
(Click in the image to download the Windows power plan settings explorer utility)

IF want the details, look at
https://youtu.be/n9xAG3nb9XQ
Also unselect "Processor idle demote/promote threshold"
and set the AC value = 100 for
BOTH "Processor idle demote/promote threshold"
- PCI Express Link State Power Management = OFF
- Go to Settings>Personalization>Colors = Disable Transparency Effects
- Go to Settings>System>Multitasking = Disable Snap Windows
- For the drives, enable the "Turn off Windows write-cache buffer flushing on the device"
Step 1. Press Win + R to open the Run dialog.
Step 2. Type devmgmt.msc and hit Enter to launch Device Manager.
Step 3. Expand Disk drives and right-click on the disk drive you want to enable/disable disk write caching to choose Properties. Here, we select an internal storage drive.
Step 4. Under the Policies tab, choose from "Enable write caching on the device" and "Turn off Windows write-cache buffer flushing on the device".
- Reboot and verify if it is better
- Now Create a second System Restore Point
https://www.elevenforum.com/t/create...ndows-11.3602/
- Disable Threaded DPCs(Windows XP behavior).
https://learn.microsoft.com/en-us/wi...-threaded-dpcs
Open Powershell as Admin. Copy/Paste/Enter the following:
reg add "HKLM\System\CurrentControlSet\Control\Session Manager\kernel" /v ThreadDpcEnable /t REG_DWORD /f /d 0
Or double click the REG file
https://drive.google.com/file/d/1Om1...usp=drive_link
- Reboot and verify if it is better.
UPDATE
I forgot the principal...
Does the sampling rate and ASIO buffer was the same?
Verify if the RME firmware is updated.
What chipset does the FireWire card uses?