Let's do a '22 edition of this very popular thread from '19 (bka 2019):

1) Softube Weiss Suite (esp. DeEss, DS1-MK3, and EQ1)

2) Chandler Limited Suite (esp. Curve Bender & Germanium Compressor)

3) Tone Projects Unisum

4) Sonible smart:limit

5) Kush Audio BLYSS

6) GBsoundLabs SweetPressor

7) Pulsar Modular P42 Climax

8) SubMission Audio Flatline

9) Oversampled\Spectral Pancz

10) KONTAKT VSTi

11) Omnisphere 2.8+ VSTi

12) Softube Drawmer 1973

13) Softube Tape

14) Leapwing Audio DynOne v3

15) Waves X-Noise | iZotope RX Specral DeNoise

Fabfilter.

Them.

I simply cannot live without them now I have them. They have made a massive difference to my workflow.