I run a 2006 Mac Pro running OS 10.6.8, Pro Tools 9.0.6 and a Tascam DM3200 running 1.70 and I don't have any problems. Originally, I upgraded my Mac Pro to Snow Leopard 10.6.3 and eventually upgraded to 10.6.8. With Pro Tools I started with M-Powered System 7, which I updated to Pro Tools 9.03 I eventually updated Pro Tools to 9.0.6 and I have been running this system for the last 18 years. 4 weeks ago my OS harddrive "Crashed & Burned" and I bought a new 2T Seagate Hard Drive and I re-installed all the software into my 2006 Mac Pro and it is up and running again. If you have issues reinstall the Mac OS update 10.6.8 and the Pro Tools update 9.0.6. I usually run the 10.6.8 and 9.0.6 updates once every 2 months to keep the programs running clean and more efficiently. I hope this helps.