There is absolutely no reason for monos to exist except for price. And modulars are stupid (and stupidly expensive for a full rig). They are basically only good (really good) for sound design.
I have several monos: Sequential Pro One (the original), Waldorf Pulse 1 and 2, Moog Subsequent 25, Minitaur, and Slim Phatty (I'm selling the Minitaur and Slim Phatty now that I have the Subsequent 25) and my favorite of all, the cheap little DiY kit the Shruthi from Mutable Instruments. As an aside, the same people who laughed at the Shruthi and said it sounded like crap ate up Mutable's Eurorack digital oscillator that was based on much of the same technology. F-ing snobbish modular weenies. They are beyond ridiculous.
Anyway, as much as I like the sound of my monos (which is the only reason I own them,) every time I call up a patch on one of these units I immediately want to play chords (except of course for bass sounds). And so I get frustrated. I'm like WTF?, I can play only one note at a time! Even more frustrating, because the Pro One doesn't have patch storage, I never actually use it in a song even though it sounds fantastic. I just extensively multisample Pro One patches that I can then play back either monophonically or polyphonically in Kontakt. And I can call up the same patch and have it sound identical to the last time I used it whenever I want.